We develop adaptable hydrogels that can hold and release in situ active molecules.

Our two-step solution is prepackaged into two ready-to-use disposable syringes.

The two-step solution is prepackaged into two ready-to-use disposable syringes. The first syringe contains a highly biocompatible hydrogel in which an antiseptic, antibiotic, active ions or active molecules are incorporated. The second syringe consists of a crosslinking agent that converts the gel into a rubbery compound, which then robustly adheres to soft and hard tissues.

Upon application, the hydrogel releases the active substance onto the tissue in a controlled manner, allowing for a remarkable increase in the local bioavailability of the active molecule, otherwise unable to enter the local circulation and tissues. The crosslinking agent allows for the prolonged release of the active substance into the local environment over an adjustable period of between two weeks to several months.

Once the hydrogel is applied to the target area and the crosslinker is applied to rapidly transform the hydrogel into the final product, the target area is essentially “sealed,” releasing the active substance only where needed and protecting the target area against intrusion by foreign particles.